M. Ward

The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms.

This study identifies distinct gene expression patterns in Chlamydia trachomatis developmental stages and shows T3SS genes are cell type restricted.

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

This study compares five CTC isolation technologies in lung cancer, finding CellMag and Parsortix PR1 have the highest recovery rates.

The impacts of contemporary logging after 250 years of deforestation and degradation on forest-dependent threatened species

This study quantifies historical and contemporary impacts of deforestation and logging on forest-dependent threatened species in New South Wales, showing significant habitat loss and degradation.

Proline catabolism is key to facilitating Candida albicans pathogenicity

This study shows that proline catabolism is essential for Candida albicans pathogenicity, as mutations in proline utilization genes reduce virulence in animal models.

A report card methodology to showcase progress towards threatened species recovery

This paper introduces a report card methodology to assess progress in threatened species recovery in Australia, revealing poor performance across key indicators.

Predicting the locations of cryptic pockets from single protein structures using the PocketMiner graph neural network

The paper introduces PocketMiner, a graph neural network that predicts cryptic pockets in proteins, identifying them accurately and rapidly, expanding the druggable proteome.

CD39 Identifies Tumor-Reactive CD8 T cells in Patients With Lung Cancer

This study identifies CD39 as a marker for tumor-reactive CD8 T cells in lung cancer, showing its association with clinical outcomes and response to immune checkpoint therapy.

Matrix stiffness and blood pressure together regulate vascular smooth muscle cell phenotype switching and cofilin dependent podosome formation

This study shows that matrix stiffness and blood pressure together drive vascular smooth muscle cell phenotypic switching and cofilin-dependent podosome formation in atherosclerosis.

Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans

This study shows that Gdh2-dependent alkalization is not required for C. albicans to escape macrophages or maintain virulence, challenging the existing model of amino acid catabolism in phagosomes.

Stat2 loss disrupts damage signalling and is protective in acute pancreatitis

This study shows that Stat2 deficiency protects against acute pancreatitis by disrupting damage signaling pathways independent of type I interferon, with reduced cytokine levels and NF-κB activation.

Mitochondrial proline catabolism activates Ras1/cAMP/PKA-induced filamentation in Candida albicans

This study shows that mitochondrial proline metabolism via PUT1 and PUT2 enhances ATP production, activates the Ras1/cAMP/PKA pathway, and promotes filamentation in C. albicans, contributing to virulence.