Cancer BiologybioRxiv
The protective effect of aspirin in colorectal carcinogenesis: a multiscale computational study from mutant evolution to age incidence curves
Y. Wang, C. R. Boland, A. Goel…·N. Komarova
This study uses mathematical models to show that aspirin-induced changes in tumor cell fitness can explain reduced colorectal adenoma incidence in treated patients.
DOI 10.7554/elife.71953