Author

A. Goel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 7 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

B. Ateeq· 3 shared N. Gupta· 2 shared N. Palanisamy· 2 shared S. Carskadon· 2 shared A. Bajpai· 1 shared A. G. Goodman· 1 shared A. Gupta· 1 shared A. Oh· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCancer Biology

B. Ateeq

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

An integrative proteomics approach identifies tyrosine kinase KIT as a novel therapeutic target for SPINK1-positive prostate cancer.

N. Manzar, U. K. Khan, A. Goel, S. Carskadon, N. Gupta, N. Palanisamy, B. Ateeq

The paper identifies KIT as a therapeutic target for SPINK1-positive prostate cancer through integrative proteomics and shows KIT inhibition reduces tumor growth and metastasis.

bioRxiv · Jul 24, 2023Cancer Biology

Distinct senescence mechanisms restrain progression of dysplastic nevi

F. K. Lorbeer, G. Rieser, A. Goel, M. Wang, A. Oh, I. Yeh, B. C. Bastian, D. Hockemeyer

The paper investigates the role of TERT promoter mutations in dysplastic nevi and their association with senescence mechanisms and progression to melanoma.

bioRxiv · Jul 14, 2023Cancer Biology

The protective effect of aspirin in colorectal carcinogenesis: a multiscale computational study from mutant evolution to age incidence curves

Y. Wang, C. R. Boland, A. Goel, D. Wodarz, N. Komarova

This study uses mathematical models to show that aspirin-induced changes in tumor cell fitness can explain reduced colorectal adenoma incidence in treated patients.

bioRxiv · May 11, 2021Cancer Biology

Nuclear biocondensate-forming lncRNA and cellular stress surveillance shape host cancer susceptibility

A. Bajpai, Q. T. Ahmad, S. Kundu, R. K. Pandey, A. G. Goodman, A. Goel, B. Ateeq, S. C. Lakhotia, P. Sinha

This study identifies hsr{omega} and its human homologs as key regulators of cancer susceptibility through stress response pathways in Drosophila and humans.

bioRxiv · Apr 26, 2021 · PreprintCancer Biology

Development of a rapid LC-MS/MS method for the simultaneous quantification of various flavonoids and phytohormones extracted from Medicago Truncatula leaves

N. Singh, N. Sharma, N. Bisht, A. Gupta, P. Awasthi, A. Goel, D. Chandran

The paper develops and validates an HPLC-MS/MS method to rapidly quantify nine flavonoids and two phytohormones in Medicago truncatula leaf extracts.

bioRxiv · Apr 14, 2021Biochemistry

Identification of novel alternative splicing events associated with tumorigenesis, protein modification, and immune microenvironment in early-onset gastric cancer

J. Zhang, A. Goel, L. Zhu

The paper identifies novel alternative splicing events in early-onset gastric cancer and links them to protein modification and immune microenvironment changes.

bioRxiv · Aug 22, 2020Cancer Biology

Epigenetic silencing of miRNA-338-5p and miRNA-421 drives SPINK1-positive prostate cancer.

V. Bhatia, A. Yadav, R. Tiwari, S. Nigam, S. Goel, S. Carskadon, N. Gupta, A. Goel, N. Palanisamy, B. Ateeq

This study identifies miRNA-338-5p and miRNA-421 as epigenetically silenced in SPINK1-positive prostate cancer, and shows their restoration inhibits oncogenic properties.

bioRxiv · Oct 2, 2018Cancer Biology

Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors

Y. Dunkel, J. Ear, Y. Mittal, B. Lim, L. Liu, M. Holda, U. Nitsche, J. Barbazan, A. Goel, K.-P. Janssen, N. Aznar, P. Ghosh

The paper identifies two Daple/CCDC88C isoforms, showing they cooperatively suppress tumor growth but only the full-length isoform triggers EMT and invasion, with aspirin affecting their expression.

bioRxiv · May 2, 2018Cancer Biology