Author

C. R. Gignoux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

G. F. Harrison· 2 shared P. J. Norman· 2 shared B. A. Lie· 1 shared D. Vukcevic· 1 shared E. A. Harrison· 1 shared G. Sun· 1 shared G. Zhang· 1 shared H. Zou· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

G. F. Harrison

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2 papers

Recent·Most cited

ImmunologyPLOS Computational BiologyPeer-reviewedFeb 22, 2022

Allele imputation for the Killer cell Immunoglobulin-like Receptor KIR3DL1/S1

G. F. Harrison, L. A. Leaton, E. A. Harrison…·P. J. Norman

This paper develops PONG, a method to impute KIR3DL1/S1 alleles from whole-genome SNP data with high accuracy across populations, enabling large-scale genetic studies.

DOI 10.1371/journal.pcbi.1009059

humanwhole-genome sequencing

𝕏 PostBluesky

ImmunologybioRxivJul 29, 2020

Genetically Determined Strength of Natural Killer Cells is Enhanced by Adaptive HLA class I Admixture in East Asians

Z. Deng, J. Zhen, G. F. Harrison…·P. J. Norman

The paper shows that East Asian populations, particularly the Chinese Southern Han, have enhanced NK cell strength due to genetic admixture and natural selection of HLA class I alleles that interact with inhibitory KIR receptors.

DOI 10.1093/molbev/msab053

humanDNA methylation

𝕏 PostBluesky