Author

J. Zhen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

C. R. Gignoux· 1 shared G. F. Harrison· 1 shared G. Sun· 1 shared G. Zhang· 1 shared H. Huang· 1 shared H. Zhou· 1 shared H. Zou· 1 shared J. A. Shortt· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

C. R. Gignoux

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

J. Zhen, J. Chen, H. Huang, S. Liao, S. Liu, Y. Yuan, R. Sun, T.-T. Wu, R. Longnecker, H. Zhou

This study uses cryoET and deep learning to reveal structural differences in the tegument and envelope of EBV and KSHV virions compared to other herpesviruses.

bioRxiv · Jul 9, 2024Microbiology

Genetically Determined Strength of Natural Killer Cells is Enhanced by Adaptive HLA class I Admixture in East Asians

Z. Deng, J. Zhen, G. F. Harrison, G. Zhang, R. Chen, G. Sun, Q. Yu, N. Nemat-Gorgani, L. A. Guethlein, L. He, M. Tang, X. Gao, S. Cai, J. A. Shortt, C. R. Gignoux, , P. J. Norman

The paper shows that East Asian populations, particularly the Chinese Southern Han, have enhanced NK cell strength due to genetic admixture and natural selection of HLA class I alleles that interact with inhibitory KIR receptors.

bioRxiv · Jul 29, 2020Immunology