Author

C. R. Troll

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. D'Souza· 1 shared A. M. Blee· 1 shared H.-S. Kim· 1 shared J. Park· 1 shared K. S. Gallagher· 1 shared M. Kim· 1 shared O. D. Schärer· 1 shared P. D. Neufer· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. D'Souza

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1 paper

Recent·Most cited

Cancer BiologybioRxivJun 29, 2023

XPA tumor variants lead to defects in NER that sensitize cells to cisplatin

A. M. Blee, K. S. Gallagher, H.-S. Kim…·W. J. Chazin

This study identifies XPA tumor variants that impair NER, increasing cisplatin sensitivity, and provides mechanistic insights for variant effect prediction.

DOI 10.1093/narcan/zcae013

humanproteomics

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