H.-S. Kim

Insects visit Fusarium xyrophilum pseudoflowers on the host Xyris surinamensis (Xyridaceae) and carry fungal DNA on their bodies

The paper investigates whether Fusarium xyrophilum pseudoflowers attract insects for dispersal by analyzing insect visitation, fungal DNA on insects, and volatile compounds.

Genome-informed trophic classification and functional characterization of virulence proteins from the maize tar spot pathogen Phyllachora maydis

This study uses a genome-informed approach to classify the trophic lifestyle of Phyllachora maydis and functionally characterize its effector proteins.

XPA tumor variants lead to defects in NER that sensitize cells to cisplatin

This study identifies XPA tumor variants that impair NER, increasing cisplatin sensitivity, and provides mechanistic insights for variant effect prediction.

Extracellular vesicle-mediated Transfer of miR-1 from Primary tumor Repress Metastasis Growth

This study shows that primary tumor-derived extracellular vesicles containing miR-1 suppress metastasis by inducing DNA damage and inhibiting cell cycle progression.

A low-power communication scheme for wireless, 1000 channel brain-machine interfaces

This paper evaluates a pulse-interval modulation (PIM) communication scheme for wireless brain-machine interfaces, finding it reduces power consumption while maintaining accurate neural signal transmission.

Dual transcriptional analysis of Peronospora belbahrii and Ocimum basilicum in susceptible interactions

The paper analyzes transcriptomes of Peronospora belbahrii and Ocimum basilicum during infection, identifying differentially expressed genes and pathways involved in defense and pathogen growth.

Arf6 anchors Cdr2 nodes at the cell cortex to control cell size at division

This study identifies Arf6 as an anchor for Cdr2 nodes at the cell cortex, essential for surface area-based size control in fission yeast.

A noble TGF beta biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

This paper identifies ONG41008 as a TGFβ biogenesis inhibitor with potent anti-fibrotic and anti-inflammatory effects in IPF and inflammatory models.

Dendrimer-like supramolecular assembly of proteins with a tunable size and valency through stepwise iterative growth

This paper introduces a programmable method to create tunable, multi-valent protein assemblies called prodrimers, showing enhanced binding affinity and cytotoxicity.

A small molecule that promotes cellular senescence prevents fibrogenesis and tumorigenesis in vitro

ONG41008 induces senescence and kills fibrotic and cancer cells without harming normal cells, suggesting it could treat fibrotic and tumorigenic diseases.

Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2

The paper computationally designs and improves a protein binder targeting HER2 domain IV, achieving a two-orders-of-magnitude increase in binding affinity through iterative computational and experimental feedback.

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

This study identifies the Btk SH2-kinase interface as critical for activation and shows that targeting it with a repebody inhibits B-cell neoplasms.

Transcriptome responses associated with carbon and energy flows under high salinity stress suggest the overflow of acetyl-CoA from glycolysis and NADPH co-factor induces high lipid accumulation and halotolerance in Chlorella sp. HS2

This study identifies transcriptome changes in Chlorella sp. HS2 under high salinity stress, revealing lipid accumulation and halotolerance mechanisms through carbon reallocation and NADPH co-factor regulation.

Development of three-dimensional articular cartilage construct using silica nano-patterned substrate

This study develops a 3D spheroid culture system using silica nano-patterned substrates to enhance the chondrogenic differentiation of fetal cartilage-derived progenitor cells.

Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling

This study identifies the fibronectin type III and intracellular domains of Tril as essential for its function in Smad7 degradation and signaling during Xenopus embryogenesis.