C. Reardon

A novel functional gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types

This paper develops a gene delivery vector based on a human anellovirus, demonstrating transduction in multiple tissues and durable in vivo function in mice.

TRPV1 controls innate immunity during Citrobacter rodentium enteric infection

This paper shows TRPV1 regulates immune responses to Citrobacter rodentium infection by modulating neutrophil recruitment through chemokine and adhesion molecule expression.

Neonatal enteropathogenic Escherichia coli infection disrupts microbiota-gut-brain axis signaling

This study shows that neonatal EPEC infection in mice impairs the microbiota-gut-brain axis, leading to cognitive deficits and intestinal inflammation in adulthood.

Nod-like receptors are critical for gut-brain axis signaling

This study identifies Nod1 and Nod2 as critical regulators of gut-brain axis signaling, showing their role in stress-induced behavioral and physiological changes.

Multiple large-scale gene and genome duplications during the evolution of hexapods

The paper investigates ancient whole genome duplications in hexapods using transcriptomes and genomes from over 150 insect species, finding 18 WGDs and six other large-scale gene duplication bursts.