BiochemistrybioRxiv
Structure of the Human Volume Regulated Anion Channel
J. M. Kefauver, K. Saotome, A. E. Dubin…·A. Patapoutian
The paper reports the high-resolution cryo-EM structure of human SWELL1, revealing its trimer of dimers assembly and identifying a charged residue critical for pore function in VRAC.