MicrobiologybioRxiv
Genetic depletion studies define receptor usage by virulent hantaviruses in human endothelial cells
M. E. Dieterle, C. Sola-Riera, R. K. Jangra…·K. Chandran
This study uses CRISPR/Cas9 to knock out potential hantavirus receptors in human endothelial cells, finding that PCDH1 is critical for some hantaviruses while other receptors like integrins and DAF are not essential.
DOI 10.7554/elife.69708