Author

C. Spaulding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

H. Teimouri· 3 shared A. B. Kolomeisky· 2 shared H. G. Munshi· 2 shared M. A. Shields· 2 shared T. N. Pham· 2 shared A. E. Metropulos· 1 shared A. Kolomeisky· 1 shared C. Li· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

H. Teimouri

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss.

M. A. Shields, A. E. Metropulos, C. Spaulding, T. Hirose, S. Ohno, T. N. Pham, H. G. Munshi

This study shows that BET inhibition rescues ciliogenesis and reduces pancreatitis-induced damage in mice with Par3 loss.

bioRxiv · Sep 14, 2023 · PreprintPathology

Theoretical understanding of evolutionary dynamics on inhomogeneous networks

H. Teimouri, D. S. Khavas, C. Spaulding, C. Li, A. Kolomeisky

The paper investigates the microscopic mechanisms of mutation fixation on inhomogeneous networks, focusing on star networks, and explains fixation probabilities and times using physics-inspired free-energy landscape arguments.

bioRxiv · Feb 2, 2023Biophysics

Optimal pathways control fixation of multiple mutations during cancer initiation

H. Teimouri, C. Spaulding, A. B. Kolomeisky

The paper presents a theoretical framework to analyze cancer initiation dynamics, showing that few dominant pathways control mutation fixation during tumor formation.

bioRxiv · Feb 7, 2022Biophysics

The Role of Extended Range of Interactions in the Dynamics of Interacting Molecular Motors

C. Spaulding, H. Teimouri, S. L. Narasimha, A. B. Kolomeisky

This study investigates how the range of interactions affects the dynamics of molecular motors using a theoretical model and simulations.

bioRxiv · Nov 9, 2021Biophysics

Gα13 loss promotes tumor progression in the KPC transgenic mouse model of advanced pancreatic cancer

M. A. Shields, C. Spaulding, M. G. Khalafalla, T. N. Pham, H. G. Munshi

The paper shows that Gα13 loss promotes tumor progression in the KPC mouse model of advanced pancreatic cancer but not in the KC model, with increased tumor burden and reduced survival.

bioRxiv · Mar 15, 2021Cancer Biology