S. Ohno

Bidirectional feedforward regulatory loop of Dicer-like 4 and flavonoids causes floral bicolor patterning in petunia and dahlia

The paper identifies a bidirectional feedforward loop between Dicer-like 4 and flavonoids that regulates RNAi and anthocyanin biosynthesis, leading to floral bicolor patterning in petunia and dahlia.

BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss.

This study shows that BET inhibition rescues ciliogenesis and reduces pancreatitis-induced damage in mice with Par3 loss.

Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.

This study identifies four conserved cysteine residues in KSHV ORF34 essential for vPIC formation and viral production through alanine-scanning mutants and structural modeling.

Dual Impacts of a Glycan Shield on the Envelope Glycoprotein B of HSV-1: Evasion from Human Antibodies In Vivo and Neurovirulence

This study identifies an N-glycan shield on HSV-1 gB that mediates evasion from human antibodies in vivo and contributes to neurovirulence.

Identification of a novel chalcone reductase gene for isoliquiritigenin biosynthesis in dahlia (Dahlia variabilis)

This study identifies a novel chalcone reductase gene (DvCHR) in dahlia involved in isoliquiritigenin biosynthesis, showing evolutionary divergence from legume CHR genes.

Enhanced CICR activity reduces ER Ca2+ level in cells expressing CPVT-linked mutant RyR2

This paper quantitatively examines how CPVT-linked RyR2 mutations affect ER Ca2+ release threshold by measuring CICR activity and simulating cellular responses.

Phosphorylation and dephosphorylation of Ser852 and Ser889 control clustering, localization, and function of PAR-3

This study shows that phosphorylation and dephosphorylation of PAR-3 at Ser852 and Ser889 regulate its clustering, localization, and function in cell polarity and junction formation.

A new role for histone demethylases in the maintenance of plant genome integrity

This study identifies ELF6 and REF6 as JMJ histone demethylases in Arabidopsis that maintain H3K27me3 and H3K27me1 homeostasis, preventing epigenetic imprints and transposon activation during sexual reproduction.

A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment

This study compares the epigenetic features of KSHV and MHV-68, showing that KSHV rapidly recruits polycomb repressive complexes through specific cis-acting sequence features, unlike MHV-68.