Author

C. Speckmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Alvarez-Prado· 1 shared A. Durandy· 1 shared B. Grimbacher· 1 shared C. Klemann· 1 shared C. Plass· 1 shared D. Weichenhan· 1 shared E. Ballestar· 1 shared F. Catala-Moll· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Alvarez-Prado

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1 paper

Recent·Most cited

Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction

F. Catala-Moll, D. Weichenhan, P. Lutsik, A. Alvarez-Prado, J. Rodriguez-Ubreva, C. Klemann, C. Speckmann, H. Abolhassani, M. Martinez-Gallo, R. Dieli-Crimi, P. Soler-Palacin, S. Kracker, L. Hammarstrom, A. Durandy, B. Grimbacher, , E. Ballestar

This study investigates AID's role in DNA methylation defects in HIGM2 B cells, finding that AID is not directly involved in active demethylation but TET enzymes are, and that methylation defects are linked to premature BCR activation.

bioRxiv · Aug 16, 2019Immunology