Author

B. Stauffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Physiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Yu· 4 shared S. M. Houten· 3 shared H. Chen· 2 shared J. Leandro· 2 shared P. Ranea-Robles· 2 shared R. J. DeVita· 2 shared T. Dodatko· 2 shared A. Bender· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

C. Yu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Acyl-CoA dehydrogenase substrate promiscuity limits the potential for development of substrate reduction therapy in disorders of valine and isoleucine metabolism

S. M. Houten, T. Dodatko, W. Dwyer, H. Chen, B. Stauffer, R. J. DeVita, F. M. Vaz, C. Yu, J. Leandro

This study investigates whether inhibiting ACAD8 and SBCAD can reduce toxic metabolite accumulation in valine and isoleucine metabolism disorders, finding that MCPA inhibits multiple ACADs and partially rescues lipoylation defects in ECHS1-deficient cells.

bioRxiv · Nov 22, 2022Biochemistry

A mitochondrial long-chain fatty acid oxidation defect leads to uncharged tRNA accumulation and activation of the integrated stress response in the mouse heart

P. Ranea-Robles, N. N. Pavlova, A. Bender, A. S. Pereyra, J. M. Ellis, B. Stauffer, C. Yu, C. B. Thompson, C. Argmann, M. A. Puchowicz, S. M. Houten

Cardiovascular Research · Apr 7, 2022Peer-reviewedPhysiology

The peroxisomal transporter ABCD3 plays a major role in dicarboxylic fatty acid metabolism

P. Ranea-Robles, H. Chen, B. Stauffer, C. Yu, D. Bhattacharya, S. L. Friedman, M. Puchowicz, S. Houten

This study investigates the role of ABCD3 in DCA metabolism using an Abcd3 KO mouse model and shows its impact on lipid homeostasis and metabolic compartmentalization.

bioRxiv · Jul 26, 2021Physiology

Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex

J. Leandro, S. Khamrui, H. Wang, C. Suebsuwong, N. S. Nemeria, K. Huynh, M. Moustakim, C. Secor, M. Wang, T. Dodatko, B. Stauffer, C. G. Wilson, C. Yu, M. R. Arkin, F. Jordan, , S. M. Houten

This study identifies DHTKD1 inhibitors and reports its crystal structure with thiamin diphosphate, revealing how mutations affect its function and stability.

bioRxiv · Jan 20, 2020Biochemistry