BioengineeringbioRxivPreprint
Epigenetic remodeling during monolayer cell expansion reduces therapeutic potential
A. Scott, E. Casas, S. E. Schneider…·C. Neu
This study shows that mechanical memory in chondrocytes is encoded in chromatin architecture, affecting their fate and therapeutic potential after expansion.
DOI 10.1101/2021.12.14.472696