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Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

R. S. HEYDERMAN· 2 shared A. D. Hyder-Wright· 1 shared A. M. Collins· 1 shared A. Soares-Schanoski· 1 shared A. Voskamp· 1 shared B. C. Urban· 1 shared B. F. Carniel· 1 shared C. Solorzano· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

R. S. HEYDERMAN

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2 papers

Recent·Most cited

The histone demethylase KDM6B fine-tunes the host response to Streptococcus pneumoniae.

M. G. Connor, T. M. N. Camarasa, E. Patey, O. Rasid, L. Barrio, C. Weight, D. P. Miller, R. S. HEYDERMAN, R. J. Lamont, J. Enninga, M. A. Hamon

This study shows that KDM6B modulates the host response to Streptococcus pneumoniae by altering chromatin structure at the IL-11 promoter, affecting NF-κB activation.

bioRxiv · May 28, 2020Microbiology

Defining mucosal immunity using mass cytometry following experimental human pneumococcal challenge

S. P. Jochems, K. de Ruiter, C. Solorzano, A. Voskamp, E. Mitsi, E. Nikolaou, B. F. Carniel, S. Pojar, E. German, J. Reine, A. Soares-Schanoski, H. Hill, R. Robinson, A. D. Hyder-Wright, C. Weight, , D. M. Ferreira

The paper uses mass cytometry to analyze nasal immune cells after pneumococcal challenge, identifying immune changes linked to colonization and host-pathogen interactions.

bioRxiv · Feb 11, 2019Immunology