Author

A. D. Hyder-Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Solorzano· 4 shared E. Mitsi· 4 shared A. M. Collins· 3 shared D. M. Ferreira· 3 shared E. Nikolaou· 3 shared H. Hill· 3 shared J. Reine· 3 shared J. Rylance· 3 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

C. Solorzano

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Author profile →

4 papers

Recent·Most cited

Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan

J. Reine, B. F. Carniel, C. Solorzano, E. Mitsi, S. Pojar, E. Nikolau, E. L. German, A. D. Hyder-Wright, H. Hill, C. Hales, L. Brown, V. Horsley, L. Hughes, S. Zaidi, V. Connor, , S. P. Jochems

This study examines age-related changes in nasal mucosal immune composition and function, finding reduced granulocytes and T cells in young children and older adults, and links pneumococcal colonization to inflammation.

bioRxiv · Mar 14, 2019 · PreprintImmunology

Efficacy of PCV vaccine is primarily mediated by controlling pneumococcal colonisation density

E. L. German, C. Solorzano, S. Sunny, F. Dunne, J. F. Gritzfeld, E. Mitsi, E. Nikolaou, A. D. Hyder-Wright, A. M. Collins, S. B. Gordon, D. Ferreira

This study re-evaluates PCV-13 efficacy using molecular methods, finding reduced colonisation acquisition and density, suggesting vaccine impact is primarily through controlling colonisation density.

bioRxiv · Feb 14, 2019 · PreprintMicrobiology

Defining mucosal immunity using mass cytometry following experimental human pneumococcal challenge

S. P. Jochems, K. de Ruiter, C. Solorzano, A. Voskamp, E. Mitsi, E. Nikolaou, B. F. Carniel, S. Pojar, E. German, J. Reine, A. Soares-Schanoski, H. Hill, R. Robinson, A. D. Hyder-Wright, C. Weight, , D. M. Ferreira

The paper uses mass cytometry to analyze nasal immune cells after pneumococcal challenge, identifying immune changes linked to colonization and host-pathogen interactions.

bioRxiv · Feb 11, 2019Immunology

Effect of Live Attenuated Influenza Vaccine on Pneumococcal Carriage

J. Rylance, W. A. de Steenhuijsen Piters, S. Pojar, E. Nikolaou, E. German, E. Mitsi, S. Jochems, B. Carniel, C. Solorzano, J. Reine, J. Gritzfeld, M. L. J. Chu, K. Arp, A. D. Hyder-Wright, H. Hill, , D. M. Ferreira

This study tests if LAIV affects pneumococcal carriage in humans, finding transient increases in bacterial density but no overall change in acquisition rates.

bioRxiv · Jun 14, 2018Immunology