The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program
O. Burton, O. Bricard, S. Tareen, V. Gergelits, S. Andrews, C. P. Roca, C. Whyte, S. Junius, A. Brajic, E. Pasciuto, M. Ali, P. Lemaitre, S. M. Schlenner, H. Ishigame, B. Brown, , A. Liston
The paper analyzes tissue-resident regulatory T cells (Tregs) in non-lymphoid organs, showing they share phenotypes, transient residency, and TCR sequences, with tissue-agnostic re-entry capabilities.
bioRxiv · Aug 14, 2023Immunology