BiophysicsbioRxiv
Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for co-receptor discrimination
N. Tsutsumi, S. Hwang, S. Hansen…·K. C. Garcia
The paper determines the structure of a ternary Wnt-Frizzled-LRP6 complex, revealing how co-receptor discrimination occurs through specific domains.
DOI 10.1073/pnas.2218238120