Author

D. Waghray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Moeller· 1 shared C. R. Glassman· 1 shared C. Y. Janda· 1 shared D. Januliene· 1 shared G. Hummer· 1 shared H. Chen· 1 shared H. Jung· 1 shared I. L. Urbatsch· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Moeller

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2 papers

Recent·Most cited

Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for co-receptor discrimination

N. Tsutsumi, S. Hwang, S. Hansen, D. Waghray, N. Wang, Y. Miao, C. R. Glassman, N. A. Caveney, K. M. Jude, C. Y. Janda, R. Hannoush, K. C. Garcia

The paper determines the structure of a ternary Wnt-Frizzled-LRP6 complex, revealing how co-receptor discrimination occurs through specific domains.

bioRxiv · Oct 21, 2022Biophysics

Tracing the substrate translocation mechanism in P-glycoprotein

T. Gewering, D. Waghray, K. Parey, H. Jung, N. N. B. Tran, J. Zapata, P. Zhao, H. Chen, D. Januliene, G. Hummer, I. L. Urbatsch, A. Moeller, Q. Zhang

This study reveals the substrate translocation mechanism in P-glycoprotein by determining cryoEM structures and using molecular dynamics simulations to identify conformational changes in TM1 that regulate transport.

bioRxiv · Apr 28, 2022 · PreprintBiophysics