Cell BiologybioRxiv
Parkin coordinates mitochondrial lipid remodeling to execute mitophagy
C.-C. Lin, J. Yan, M. D. Kapur…·T.-P. Yao
This study shows Parkin orchestrates mitochondrial lipid remodeling through phospholipase D2 and Lipin-1 to drive mitophagy via DAG production and autophagosome formation.
DOI 10.15252/embr.202255191