Author

J.-T. Chi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

C.-C. Lin· 2 shared T.-P. Yao· 2 shared A. Lu· 1 shared A. Smith· 1 shared A. Sun· 1 shared A. Wax· 1 shared C. R. Justus· 1 shared C.-H. Lai· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

C.-C. Lin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Characterizing stored red blood cells using ultra-high throughput holographic cytometry

H. S. Park, H. Price, S. Ceballos, J.-T. Chi, A. Wax

This study uses holographic cytometry to analyze morphological changes in stored red blood cells and demonstrates its potential for diagnostic applications using machine learning.

bioRxiv · Apr 29, 2021Bioengineering

Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

C.-C. Lin, J. Yan, M. D. Kapur, K. L. Norris, C.-W. Hsieh, C.-H. Lai, N. Vitale, K.-L. Lim, Z. Guan, J.-T. Chi, W.-Y. Yang, T.-P. Yao

This study shows Parkin orchestrates mitochondrial lipid remodeling through phospholipase D2 and Lipin-1 to drive mitophagy via DAG production and autophagosome formation.

bioRxiv · Feb 28, 2020Cell Biology

RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

C.-C. Lin, N. Mabe, Y.-T. Lin, W.-H. Yang, X. Tang, L. Hong, T. Sun, T.-P. Yao, J. Alvarez, J.-T. Chi

This study identifies RIPK3 upregulation in recurrent breast tumors, showing it promotes proliferation but also creates dependence on cystine, offering new therapeutic targets.

bioRxiv · Jun 21, 2019Cancer Biology

Glycosylation of gigaxonin regulates intermediate filaments: Novel molecular insights into giant axonal neuropathy

P.-H. CHEN, T. Smith, J. Hu, S. Pan, A. Smith, A. Lu, J.-T. Chi, M. Boyce

This study identifies O-GlcNAcylation of gigaxonin as a regulatory mechanism linking metabolism to intermediate filament proteostasis, offering insights into giant axonal neuropathy.

bioRxiv · Jan 26, 2019 · PreprintCell Biology

Contextual Tumor Suppressor Function Of T Cell Death-Associated Gene 8 (TDAG8) In Hematological Malignancies

C. R. Justus, E. J. Sanderlin, L. Dong, A. Sun, J.-T. Chi, K. Lertpiriyapong, L. V. Yang

This study shows TDAG8 gene expression is reduced in blood cancers and its restoration suppresses tumor growth and metastasis under acidotic conditions.

bioRxiv · Jun 1, 2017Cancer Biology