Author

Calvin Johnson

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jason Robert PitarresiiD· 2 shared Lihua Julie ZhuiD· 2 shared Marcus A. RuscettiiD· 2 shared Nikita BhaleraoiD· 2 shared Adı́lson GuilhermeiD· 1 shared Akhila BalachanderiD· 1 shared Alicia TayiD· 1 shared Amit SinghaliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Jason Robert PitarresiORCID

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Author profile →

3 papers

Recent·Most cited

Multiplexed cytokine and antigen mRNA administration generates durable anti-tumor immunity against pancreatic cancer

Chaitanya Naimesh Parikh, Kelly D. DeMarco, Nikita Bhalerao, Hadiya K. Giwa, Griffin I. Kane, Ronnie W Dinnell, Boyang Ma, Haruka Mori, Meghan L. Brassil, Katherine C. Murphy, Zhen Zhao, Calvin Johnson, Shriram Ramani, Lin Zhou, Loretah Chibaya, , Marcus A. Ruscetti

This study shows that delivering multiple cytokine and antigen mRNAs via nanoparticles can generate strong anti-tumor immunity against pancreatic cancer in mice.

Nature Communications · Jun 19, 2026Peer-reviewedCancer Biology

NR4A1 limits CD8⁺ T Cell effector responses and protection in tuberculosis

Amit Singhal, Samreen Fatima, Yao Chen, Lorissa Smulan, Basanthi Satish, Mike Jameson, Sheetal Saini, Calvin Johnson, Alicia Tay, Shihui Foo, Hedayathulla Rahmathulla, Akhila Balachander, Shanshan Wu Howland, Hardy Kornfeld

NR4A1 suppresses CD8+ T cell infiltration and cytotoxicity in TB lesions, and its inhibition enhances host resistance to Mtb infection.

bioRxiv · Jan 13, 2026 · PreprintImmunology

Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis

Nikita Bhalerao, Yamini Ogoti, Jessica Peura, Calvin Johnson, Qingbo Chen, Ekaterina D. Korobkina, Faith N. Keller, Maximilian D. Wengyn, Robert J. Norgard, Claire Shamber, Kelsey A. Klute, Dominick J. DiMaio, Karine Sellin, Paul M. Grandgenett, Rui Li, , Jason Robert Pitarresi

This study identifies PTHrP as a driver of pancreatic cancer cachexia by suppressing adipose de novo lipogenesis, showing that blocking PTHrP-PTH1R signaling reduces wasting in mouse models.

bioRxiv · Jun 3, 2025 · PreprintCancer Biology