BiochemistrybioRxivPreprint
Cardiac contraction velocity has evolved to match heart rate with body size through variation in β-cardiac myosin sequence.
Chloe A. Johnson, Jake E. McGreig, Carlos D. Vera…·Michael A. Geeves
The paper identifies amino acid sites in β-cardiac myosin associated with body mass and shows that altering these sites can adjust contraction velocity and ADP release rate.