MicrobiologyPLoS BiologyPeer-reviewed
The Toxoplasma Oxygen Sensing Protein, TgPhyA, Is Required for Resistance to Interferon-gamma Mediated Nutritional Immunity
Charlotte Cordonnier, Msano Mandalasi, Jason P. Gigley…·Ira J. Blader
This study shows that TgPHYa, an oxygen-sensing protein in Toxoplasma, is essential for parasite virulence and survival in immune cells by enabling tryptophan scavenging during IFN-gamma-induced nutritional immunity.
6 citations