PhysiologyBiophysical JournalPeer-reviewed
Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors
Weikang Ma, Carlos L del Rio, Lin Qi…·Thomas C. Irving
This paper shows that mavacamten stabilizes myosin in off states, which can still be recruited by physiological inotropic effectors to maintain cardiac function.
8 citations