Author

Cristina Bonorino

Beth Israel Deaconess Medical CenterPrimary ORCID profile (0000-0003-2755-3978 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Cristina BonorinoiD1 paper · Universidade Federal de Ciências da Saúde de Porto Alegre

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Assay:imaging· 1

Frequent Co-Authors

Ana Paula Duarte de Souza· 1 shared Andre Bafica· 1 shared Ayesha MurshidiD· 1 shared Benjamin J. LangiD· 1 shared Daniel A. G. Bueno Mendes· 1 shared Deise Nascimento de Freitas· 1 shared Fabio Maito· 1 shared Isadora Tadeval Lape· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Ana Paula Duarte de Souza

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2 papers

Recent·Most cited

ImmunologyCell Stress and ChaperonesPeer-reviewedMay 22, 2025

Innate extracellular Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors

Thiago J. Borges, Karina Rodrigues Lima, Ayesha Murshid…·Stuart K. Calderwood

This study identifies Siglec-E and LOX-1 as receptors mediating extracellular Hsp70's inflammatory properties through their interaction on dendritic cells.

6 citations

mouseproteomics

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ImmunologybioRxivPreprintNov 8, 2017

RSV Downregulates IL-21/IL-21R On TFH Cells Via PD-L1 Induction In APCs Impairing Protective Humoral Responses

Rodrigo Benedetti Gassen, Tiago Fazolo, Deise Nascimento de Freitas…·Cristina Bonorino

This study shows RSV impairs TFH cell function by inducing PD-L1 on APCs, reducing IL-21 and its receptor, which weakens humoral immunity, but IL-21 treatment can restore immune responses and protect against RSV infection.

DOI 10.1101/203133

mouseimaging

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