K. Wynne

The paper identifies specific cPRC1 complexes, CBX4/PCGF4, that mediate oncogenic gene repression in DMG cells downstream of H3K27M mutation.

The paper identifies that PRC2 loss in T-ALL reduces WNT pathway activity, leading to asparaginase resistance, which can be overcome by proteasome inhibition.

This study shows that KSR1 is essential for maintaining the transformed phenotype of BRAFV600E mutant melanoma cells by promoting cell survival and inhibiting senescence and apoptosis.

The paper identifies novel interactions of PCGF1, PCGF2, and PCGF4 using AP-MS under endogenous conditions, revealing functional pathways and mutual regulation among these proteins.

This paper develops a deep learning method to rapidly identify mosquito species and age from mid-infrared spectra, with high accuracy for malaria vectors.

This paper uses vibrational spectroscopy to analyze G-quadruplexes and B-DNA, revealing unique low-frequency vibrational modes not predicted by current theoretical models.

This study shows that mechanically activated osteocyte-derived extracellular vesicles enhance human MSC recruitment and osteogenesis, suggesting their potential as a cell-free therapy for bone regeneration.