D. Angeletti

This study shows that loss of Lamin A causes AGO2 to move into the nucleus, impairing RNAi and increasing oncogenic miRNA expression in cancer cells.

The paper develops a tolerogenic fusion protein that reduces autoimmune disease symptoms by inducing Tr1 cells and altering cDC1 gene expression via IL-27 signaling.

The paper analyzes single-cell BCR and transcriptome data from influenza-infected mice to reveal organ-specific B cell dynamics and clonal responses.

This study shows anti-HA stem antibodies neutralize influenza A virus by inhibiting neuraminidase activity, with implications for therapeutic synergy with NA inhibitors.

This study shows that immunodominance in influenza HA can be overcome by targeting the conserved stem through specific immunization strategies.