D. B. Staroverov

This paper introduces TCR-Track, a method to map and track helper T cell subsets in scRNA-Seq data, revealing their clonal relationships and functional programs over time.

The paper analyzes longitudinal BCR repertoires to show clonal persistence and differentiation into ASCs with positive selection and affinity maturation.

The paper shows plasmids can persist in E. coli under continuous CRISPR targeting without genetic changes, due to stochastic processes and plasmid replication dynamics.

This study compares T cell receptor diversity across species, finding that long-lived rodents maintain stable TCR diversity with age, unlike humans and mice.