Repertoire-based mapping and time-tracking of helper T cell subsets in scRNA-Seq
D. K. Lukyanov, V. V. Kriukova, K. Ladell, I. A. Shagina, D. B. Staroverov, B. Minasian, A. S. Fedosova, P. Shelyakin, O. N. Suchalko, A. Komkov, K. A. Blagodatskikh, K. L. Miners, O. V. Britanova, A. Franke, D. A. Price, D. M. Chudakov
This paper introduces TCR-Track, a method to map and track helper T cell subsets in scRNA-Seq data, revealing their clonal relationships and functional programs over time.
bioRxiv · Oct 24, 2023Immunology