Author

D. Bratton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

D. Irwin· 1 shared E. Gerasimovskaya· 1 shared J. A. Monks· 1 shared K. R. Stenmark· 1 shared K. Wang· 1 shared M. A. Fini· 1 shared M. G. Frid· 1 shared M. Karin· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

D. Irwin

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1 paper

Recent·Most cited

Macrophage Xanthine Oxidoreductase Links LPS Induced Lung Inflammatory Injury to NLRP3 Inflammasome Expression and Mitochondrial Respiration

M. A. Fini, J. A. Monks, M. Li, E. Gerasimovskaya, P. Paucek, K. Wang, M. G. Frid, S. C. Pugliese, D. Bratton, Y.-R. Yu, D. Irwin, M. Karin, R. M. Wright, K. R. Stenmark

This study shows that macrophage-specific Xanthine Oxidoreductase (XOR) exacerbates LPS-induced lung injury by promoting NLRP3 inflammasome expression and glycolytic metabolism in inflammatory macrophages.

bioRxiv · Jul 21, 2023 · PreprintImmunology