Author

D. Irwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Research Focus:host-pathogen & immune response· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

A. S. Rubtsov· 2 shared E. Nikelski· 2 shared D. Bratton· 1 shared D. Schluter· 1 shared E. Gerasimovskaya· 1 shared J. A. Monks· 1 shared K. R. Stenmark· 1 shared K. Wang· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersEvolutionary Biology

A. S. Rubtsov

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Macrophage Xanthine Oxidoreductase Links LPS Induced Lung Inflammatory Injury to NLRP3 Inflammasome Expression and Mitochondrial Respiration

M. A. Fini, J. A. Monks, M. Li, E. Gerasimovskaya, P. Paucek, K. Wang, M. G. Frid, S. C. Pugliese, D. Bratton, Y.-R. Yu, D. Irwin, M. Karin, R. M. Wright, K. R. Stenmark

This study shows that macrophage-specific Xanthine Oxidoreductase (XOR) exacerbates LPS-induced lung injury by promoting NLRP3 inflammasome expression and glycolytic metabolism in inflammatory macrophages.

bioRxiv · Jul 21, 2023 · PreprintImmunology

Evidence for a chromosomal inversion maintaining divergent plumage phenotypes between extensively hybridizing yellowhammers (Emberiza citrinella) and pine buntings (E. leucocephalos)

E. Nikelski, A. S. Rubtsov, D. Irwin

The paper identifies a chromosomal inversion on the Z chromosome that maintains plumage divergence between hybridizing yellowhammers and pine buntings despite weak reproductive barriers.

bioRxiv · Jun 13, 2023 · PreprintEvolutionary Biology

Geographic variability of hybridization between Red-breasted and Red-naped Sapsuckers

L. Natola, S. M. Billerman, M. D. Carling, S. S. Seneviratne, D. Irwin

The paper examines hybridization dynamics between Red-breasted and Red-naped Sapsuckers across different geographic regions, finding variation in hybrid zone characteristics influenced by local environmental factors.

bioRxiv · Aug 1, 2022 · PreprintEvolutionary Biology

Extreme Heterogeneity in Genomic Differentiation between Phenotypically Divergent Songbirds: A Test of Mitonuclear Co-introgression

E. Nikelski, A. S. Rubtsov, D. Irwin

The paper examines mitonuclear discordance in yellowhammers and pine buntings, finding heterogeneous nuclear differentiation and evidence for mitonuclear co-introgression.

bioRxiv · Aug 8, 2021 · PreprintEvolutionary Biology

Hybridization and the coexistence of species

D. Irwin, D. Schluter

The paper models coexistence of two sympatric species with incomplete reproductive isolation, showing hybrid fitness and assortative mating influence species survival and coexistence.

bioRxiv · Apr 4, 2021Ecology