Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
J. R. Ishibashi, T. H. Taslim, A. M. Hussein, D. Brewer, S. Liu, S. Harper, B. Nguyen, J. Dang, A. Chen, D. del Castillo, J. Mathieu, H. Ruohola-Baker
The paper shows that PRC2/PRC1-mediated mitochondrial checkpoint regulates quiescence in Drosophila GSCs and human iPSCs through mitophagy and mitochondrial dynamics.
bioRxiv · Apr 21, 2021 · PreprintBiochemistry