Author

J. Dang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 2 Plant Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:metabolomics· 2

Frequent Co-Authors

C. Gamble· 2 shared D. Doughty· 2 shared S. Liu· 2 shared A. Chen· 1 shared A. M. Hussein· 1 shared A. Martinez· 1 shared A. Pollock· 1 shared A. Read· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

C. Gamble

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis

R. Liu, J. Dang, L. Rhoeun, J.-J. Lee, H. Ameri, N. Rao, H. Eoh

This study investigates the metabolic mechanisms enabling Mycobacterium tuberculosis dormancy in retinal pigment epithelium cells and proposes a therapeutic strategy using phosphoenolpyruvate to enhance antibiotic efficacy.

bioRxiv · Mar 18, 2024 · PreprintMicrobiology

Two haplotype-resolved genomes of highly heterozygous AAB allotriploid bananas provide insights into subgenome asymmetric evolution and banana wilt control

W. Xie, Y. Zheng, W. He, F. Bi, Y. Li, T. Dou, R. Zhou, Y. Guo, G. Deng, W. Zhang, M. Yuan, P. Sanz-Jimenez, X. Zhu, X. Xu, Z. Zhou, , L. Chen

This study presents haplotype-resolved genomes of triploid bananas, revealing subgenome asymmetric evolution and resistance mechanisms against banana wilt.

bioRxiv · Mar 28, 2023 · PreprintPlant Biology

An oral protein cocktail therapeutic for C. difficile infection

H. Zhao, M. Dodds, A. Pollock, M. Gewe, A. Martinez, K. Keeney, B. Jester, M. Hutton, H. Tabakh, M. Zhang, M. Heinnickel, T. Paddock, S. Ertel, K. Aggarwal, C. Amendola, , Guzma

This paper describes an oral protein cocktail, LMN-201, for C. difficile infection, showing it achieves high cure rates and validates spirulina as a delivery platform.

bioRxiv · Dec 21, 2021 · PreprintBioengineering

Machine Learning Optimization of Photosynthetic Microbe Cultivation and Recombinant Protein Production

C. Gamble, D. Bryant, D. Carrieri, E. Bixby, J. Dang, J. Marshall, D. Doughty, L. Colwell, M. Berndl, J. Roberts, M. Frumkin

This study uses machine learning to optimize culture conditions for producing therapeutic proteins in spirulina, doubling production and improving volumetric productivity by 70-100%.

bioRxiv · Aug 6, 2021 · PreprintBioengineering

Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

J. R. Ishibashi, T. H. Taslim, A. M. Hussein, D. Brewer, S. Liu, S. Harper, B. Nguyen, J. Dang, A. Chen, D. del Castillo, J. Mathieu, H. Ruohola-Baker

The paper shows that PRC2/PRC1-mediated mitochondrial checkpoint regulates quiescence in Drosophila GSCs and human iPSCs through mitophagy and mitochondrial dynamics.

bioRxiv · Apr 21, 2021 · PreprintBiochemistry

The spermidine acetyltransferase SpeG regulates transcription of the small RNA RprA

L. I. Hu, E. V. Filippova, J. Dang, S. Pshenychnyi, J. Ruan, O. Kiryukhina, W. F. Anderson, M. L. Kuhn, A. Wolfe

This study shows that SpeG, an acetyltransferase, interacts with RcsB to inhibit rprA transcription in E. coli, linking polyamine metabolism to global regulatory functions.

bioRxiv · Nov 5, 2018Microbiology

MUTE Directly Orchestrates Cell State Switch and the Single Symmetric Division to Create Stomata

S.-K. Han, X. Qi, K. Sugihara, J. Dang, T. A. Endo, K. Miller, E.-D. Kim, T. Miura, K. Torii

The paper identifies MUTE's role in orchestrating cell state switch and single symmetric division during stomatal differentiation by regulating gene expression and forming an Incoherent Type 1 Feed-Forward Loop.

bioRxiv · Mar 21, 2018Plant Biology