MicrobiologyPLOS PathogensPeer-reviewed
Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle
D. C. Badgujar, A. Anil, A. E. Green…·A. Banerjee
This paper identifies structural changes in a non-hemolytic pneumolysin variant that disable pore formation, enabling pneumococcus to adopt an intracellular lifestyle with reduced inflammation and increased host tolerance.
DOI 10.1371/journal.ppat.1009016