Author

D. C. Palmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

D. C. Deniger· 2 shared D. Gurusamy· 2 shared N. P. Restifo· 2 shared P. Malekzadeh· 2 shared R. J. Kishton· 2 shared S. J. Patel· 2 shared S. K. Vodnala· 2 shared W. Lo· 2 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

D. C. Deniger

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2 papers

Recent·Most cited

ImmunologybioRxivSep 24, 2020

Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade

D. C. Palmer, B. R. Webber, Y. Patel…·N. P. Restifo

This study shows that CISH knockout in TIL enhances neoantigen reactivity and synergizes with PD1 blockade to improve tumor regression.

DOI 10.1016/j.medj.2022.07.008

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 18, 2019

Genome-wide profiling of druggable active tumor defense mechanisms to enhance cancer immunotherapy

R. J. Kishton, S. J. Patel, S. K. Vodnala…·N. P. Restifo

This study identifies genes that tumor cells use to resist T cell killing and shows that inhibiting BIRC2, ITGAV, or DNPEP enhances T cell-mediated tumor destruction.

DOI 10.1101/843185

humanwhole-genome sequencing

𝕏 PostBluesky