ImmunologybioRxivPreprint
Allelic variation in Class I HLA determines pre-existing memory responses to SARS-CoV-2 that shape the CD8+ T cell repertoire upon viral exposure
J. M. Francis, D. Leistritz-Edwards, A. Dunn…·D. C. Pregibon
The paper characterizes CD8+ T cell responses to SARS-CoV-2 across HLA alleles, showing HLA genotype influences pre-existing immunity and immune repertoire upon viral exposure.