Cancer BiologybioRxiv
PRMT1 regulates EGFR and Wnt signaling pathways and is a promising target for combinatorial treatment of breast cancer
S. Suresh, S. Huard, A. Brisson…·T. Dubois
This study identifies PRMT1 as a key regulator of EGFR and Wnt signaling in breast cancer and shows that targeting it with inhibitors can enhance chemotherapy and EGFR inhibitor efficacy in TNBC.
DOI 10.3390/cancers14020306