Longitudinal single cell profiling of regulatory T cells identifies IL-33 as a driver of tumor immunosuppression
A. Li, R. H. Herbst, D. Canner, J. M. Schenkel, O. C. Smith, J. Y. Kim, M. Hillman, A. Bhutkar, M. S. Cuoco, C. G. Rappazzo, P. Rogers, C. Q. Dang, O. Rozenblatt-Rosen, L. Cong, M. Birnbaum, , T. Jacks
The paper identifies IL-33 as a driver of tumor immunosuppression by analyzing longitudinal single-cell RNA-Seq data of regulatory T cells in a mouse model of lung adenocarcinoma.
bioRxiv · Jan 6, 2019 · PreprintCancer Biology