Cell BiologybioRxiv
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
D. Chondronasiou, D. Gill, L. Mosteiro…·M. Serrano
This study shows that a single cycle of transient OSKM expression reverses aging-related DNA methylation, transcriptional, and metabolic changes in multiple tissues of aged mice.
DOI 10.1111/acel.13578