Lactoylglutathione promotes inflammatory signaling in macrophages
M. N. Trujillo, E. Q. Jennings, E. A. Hoffman, H. Zhang, A. M. Phoebe, G. E. Mastin, N. Kitamura, J. A. Reisz, E. Megill, D. Kantner, M. M. Marcinkiewicz, S. M. Twardy, F. Lebario, E. Chapman, R. L. McCullough, , J. J. Galligan
This study shows that lactoylglutathione (LGSH) promotes inflammatory signaling in macrophages by increasing histone lactoylation and chromatin accessibility.
bioRxiv · Oct 10, 2023 · PreprintBiochemistry