Author

D. Kantner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

E. Megill· 3 shared N. W. Snyder· 3 shared A. Chatoff· 2 shared M. M. Marcinkiewicz· 2 shared A. Amalric· 1 shared A. D'Alessandro· 1 shared A. M. Phoebe· 1 shared A. R. Cole· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

E. Megill

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

A. Uboveja, Z. Huang, R. Buj, A. Amalric, H. Wang, N. K. Tangudu, A. R. Cole, E. Megill, D. Kantner, A. Chatoff, H. Ahmad, M. M. Marcinkiewicz, J. A. Disharoon, S. Graff, E. S. Dahl, , K. M. Aird

This study shows that αKG-mediated carnitine synthesis supports HR proficiency by promoting histone acetylation, which enhances DNA repair.

bioRxiv · Feb 6, 2024Cancer Biology

Lactoylglutathione promotes inflammatory signaling in macrophages

M. N. Trujillo, E. Q. Jennings, E. A. Hoffman, H. Zhang, A. M. Phoebe, G. E. Mastin, N. Kitamura, J. A. Reisz, E. Megill, D. Kantner, M. M. Marcinkiewicz, S. M. Twardy, F. Lebario, E. Chapman, R. L. McCullough, , J. J. Galligan

This study shows that lactoylglutathione (LGSH) promotes inflammatory signaling in macrophages by increasing histone lactoylation and chromatin accessibility.

bioRxiv · Oct 10, 2023 · PreprintBiochemistry

Dynamic protein deacetylation is a limited carbon source for acetyl-CoA-dependent metabolism

I. Soaita, E. Megill, D. Kantner, A. Chatoff, Z. Arany, N. W. Snyder, K. E. Wellen, S. W. Trefely

This study shows that dynamic protein deacetylation in Acly-/- MEFs contributes carbons to acetyl-CoA but only transiently supplies about 9% of cellular acetyl-CoA.

bioRxiv · Dec 28, 2022Biochemistry