Author

M. Padi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:human· 5 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Grant· 3 shared A. D. Grant· 2 shared G. Mouneimne· 2 shared M. R. Roman· 2 shared S. S. Parker· 2 shared A. M. Wang· 1 shared A. W. Watson· 1 shared A. Witkiewicz· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

A. Grant

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma

J. Yang, J. T. Lim, P. V. Santiago Raj, M. G. Corona, C. Chen, H. Khawaja, Q. Pan, G. D. Paine-Murrieta, R. G. Schnellmann, D. J. Roe, P. C. Gokhale, J. A. DeCaprio, M. Padi

This study identifies pyrvinium pamoate as a potential therapy for Merkel cell carcinoma by targeting Wnt signaling and multiple cancer vulnerabilities.

bioRxiv · Nov 1, 2023Cancer Biology

Molecular Drivers of Tumor Progression in Microsatellite Stable APC Mutation-Negative Colorectal Cancers

A. Grant, R. M. Xicola, V. T. Nguyen, J. Lim, C. Thorne, B. Salhia, X. Llor, N. Ellis, M. Padi

The paper identifies two distinct subtypes of APC mutation-negative colorectal cancers characterized by mitochondrial activation or WNT pathway sensitivity.

bioRxiv · Sep 14, 2021Cancer Biology

EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in developing neurons

S. S. Parker, K. T. Ly, A. D. Grant, A. M. Wang, J. D. Parker, M. R. Roman, M. Padi, C. W. Wolgemuth, P. R. Langlais, G. Mouneimne

This study identifies EVL's role in regulating dendritic filopodia morphology and dynamics through its interaction with MIM/MTSS1, promoting actin remodeling in developing neurons.

bioRxiv · May 26, 2021Cell Biology

Cell intrinsic signaling in MEN1 mutant pancreatic neuroendocrine tumors unveils novel signaling pathways associated with de-differentiation

B. A. Rheinheimer, R. L. Heimark, A. D. Grant, L. Camacho, M. Padi, T. Jie

The paper identifies MEN1 and FGFR3 mutations in pancreatic neuroendocrine tumors and links them to de-differentiation and aggressiveness, suggesting FGFR3 as a therapeutic target.

bioRxiv · Sep 29, 2020 · PreprintCancer Biology

Breast tumor stiffness instructs bone metastasis via mechanical memory

A. W. Watson, A. Grant, S. S. Parker, M. W. Harman, M. R. Roman, B. L. Forte, C. C. Gowan, R. Castro-Portuguez, C. Franck, D. Cusanovich, M. Padi, C. Romanoski, G. Mouneimne

This study shows that primary tumor stiffness induces stable mechanical memory in breast cancer cells, promoting bone metastasis through ERK-RUNX2 signaling and a MeCo score.

bioRxiv · Nov 20, 2019 · PreprintCancer Biology

Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations

A. Grant, P. Vail, M. Padi, A. Witkiewicz, E. Knudsen

The paper introduces MAXX, a tool to analyze allelic expression of mutations in cancer, identifying driver mutations and prognostic subtypes in PDAC.

bioRxiv · Aug 17, 2018Cancer Biology