2'-O -methylation of the second transcribed nucleotide within mRNA 5' cap impacts protein production level in a cell specific manner and contributes to RNA immune evasion
K. Drazkowska, N. Baran, M. Warminski, R. Tomecki, A. Depaix, D. Cysewski, R. Kasprzyk, J. Kowalska, J. Jemielity, P. J. Sikorski
This study shows that 2'-O-methylation of the second transcribed nucleotide in mRNA 5' cap affects protein production levels and contributes to RNA immune evasion in a cell-specific manner.
bioRxiv · Feb 3, 2022Biochemistry