The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments
T. Stephan, S. Stoldt, M. Barbot, T. D. Carney, F. Lange, M. Bates, P. Bou Dib, H. Shcherbata, M. Meinecke, D. Riedel, S. Dennerlein, P. Rehling, S. Jakobs
This study identifies DmMIC10b as the major MIC10 orthologue in Drosophila, showing it polymerizes into cristae-shaping filaments that affect mitochondrial structure and fly lifespan.
bioRxiv · Apr 17, 2023 · PreprintCell Biology