Author

P. Rehling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1

Frequent Co-Authors

A. Chacinska· 2 shared K. Mohanraj· 2 shared L. D. Cruz-Zaragoza· 2 shared S. Dennerlein· 2 shared S. Jakobs· 2 shared A. D. Davidson· 1 shared A. E. Firth· 1 shared A. Gosk· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

A. Chacinska

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments

T. Stephan, S. Stoldt, M. Barbot, T. D. Carney, F. Lange, M. Bates, P. Bou Dib, H. Shcherbata, M. Meinecke, D. Riedel, S. Dennerlein, P. Rehling, S. Jakobs

This study identifies DmMIC10b as the major MIC10 orthologue in Drosophila, showing it polymerizes into cristae-shaping filaments that affect mitochondrial structure and fly lifespan.

bioRxiv · Apr 17, 2023 · PreprintCell Biology

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity

H. Stewart, Y. Lu, S. O'Keefe, A. Valpadashi, L. D. Cruz-Zaragoza, H. A. Michel, S. K. Nguyen, G. W. Carnell, N. Lukhovitskaya, R. Milligan, I. Jungreis, V. Lulla, A. D. Davidson, D. A. Matthews, S. High, , A. E. Firth

This study identifies ORF3c as a SARS-CoV-2 protein that localizes to mitochondria and inhibits IFN-β production without affecting NF-κB or JAK-STAT signaling.

bioRxiv · Nov 15, 2022Microbiology

A quantitative fluorescence-based approach to study mitochondrial protein import

N. Jain, R. Gomkale, O. Bernhard, P. Rehling, L. D. Cruz-Zaragoza

This paper introduces a fluorescence-based method for analyzing mitochondrial protein import with high sensitivity and quantification capabilities.

bioRxiv · Oct 10, 2022Biochemistry

Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel metazoan specific complex III assembly factor

K. J. Chojnacka, K. Mohanraj, S. Callegari, B. H. M. Mussulini, P. Elanchelyan, A. Gosk, T. Banach, T. Goral, P. Rehling, R. A. Serwa, A. Chacinska

This study identifies OCIAD2 as a novel metazoan-specific complex III assembly factor, showing its role in mitochondrial function and its deregulation in cancer and neurodegenerative disorders.

bioRxiv · Dec 9, 2020 · PreprintCell Biology

Local translation in synaptic mitochondria influences synaptic transmission

R. Yousefi, E. F. Fornasiero, L. Cyganek, S. Jakobs, S. O. Rizzoli, P. Rehling, D. Pacheu Grau

The paper uses an imaging approach to study mitochondrial translation in neurons, finding it occurs in dendrites and axons, correlates with synaptic activity, and affects synaptic function.

bioRxiv · Jul 22, 2020 · PreprintBiochemistry

Inhibition of proteasomal degradation rescues a pathogenic variant of mitochondrial Respiratory chain assembly 1 factor

K. Mohanraj, M. Wasilewski, C. Beninca, D. Cysewski, J. Poznanski, P. Sakowska, M. Deckers, S. Dennerlein, E. Fernandez-Vizarra, P. Rehling, M. Dadlez, M. Zeviani, A. Chacinska

This study shows that inhibiting proteasome degradation rescues mutant RESA1 protein function and complex IV activity in patient-derived fibroblasts.

bioRxiv · Jul 24, 2018Biochemistry