Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery
L. M. Sipe, M. Chaib, E. B. Korba, M. C. Lovely, H. Jo, B. R. Counts, U. Tanveer, J. C. Clements, N. A. John, D. Daria, T. N. Marion, R. Sekhri, A. K. Pingili, B. Teng, J. A. Carson, , L. Makowski
This study shows that bariatric surgery followed by immune checkpoint blockade improves breast cancer outcomes in formerly obese mice, despite weight loss being less effective than diet in reducing tumor burden.
bioRxiv · Mar 30, 2022Cancer Biology