Author

D. De Tommaso

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Amedei· 1 shared A. Naldini· 1 shared A. Taddei· 1 shared C. Cassioli· 1 shared C. T. Baldari· 1 shared C. Ulivieri· 1 shared F. Carraro· 1 shared F. Coppola· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Amedei

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1 paper

Recent·Most cited

Cancer BiologybioRxivJun 23, 2023

Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

T. Montecchi, G. Nannini, D. De Tommaso…·C. Ulivieri

This study identifies Rai as a novel HIF-1-responsive gene upregulated in CRC TILs, which promotes T cell exhaustion by sustaining GSK-3 activation and PD-1 expression.

DOI 10.1007/s00262-023-03614-0

humanbulk RNA-seq

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