Author

D. Despotopoulou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Kostarelos· 2 shared M. Stylianou· 2 shared N. Lozano· 2 shared T. Kisby· 2 shared A. S. MacDonald· 1 shared A. Thawley· 1 shared H. Parker· 1 shared K. Arashvand· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

K. Kostarelos

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2 papers

Recent·Most cited

BioengineeringCell Reports Physical SciencePeer-reviewedJan 1, 2025

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

M. Stylianou, T. Kisby, D. Despotopoulou…·K. Kostarelos

This paper demonstrates that graphene oxide nanosheets loaded with a TLR7/8 agonist can reprogram tumor-associated macrophages in GBM to a pro-inflammatory state, reducing tumor burden.

DOI 10.1016/j.xcrp.2024.102342

mouseproteomics

𝕏 PostBluesky

BioengineeringbioRxivPreprintAug 22, 2023

Engineering of a graphene oxide-based two-dimensional platform for immune activation and modulation

D. Despotopoulou, M. Stylianou, L. M. Arellano…·K. Kostarelos

This study designs graphene oxide-based nanosheets to form stable complexes with the TLR7/8 agonist R848, preserving its biological activity and demonstrating effective macrophage activation.

DOI 10.1101/2023.08.22.553542

experimental assaydrug response / drug discovery

𝕏 PostBluesky